Recent Publications
Beyer BK, Chernoff N, Danielsson B, Davis-Bruno K, Harrouk W, Hood RD, Janer G, Liminga UW, Kim J, Rocca M, Rogers J, Scialli AR. ILSI/HESI Maternal Toxicity Workshop Summary: Maternal toxicity and its impact on study design and data interpretation. Birth Defects Res (Part B) 2011;92:36-51.
DownloadBoffetta P, Scialli AR. TCDD and birth weight of Vietnamese infants. Environ Sci Pollution Res 2016;23:17857–17858.
DownloadBridges J, Dekant W, Klaunig JE, Scialli AR. Comments on the safety assessment of decamethylcyclopentasiloxane (D5). Regul Toxicol Pharmacol 2017;89:305–306.
DownloadCarney EW, Ellis AL, Tyl RW, Foster PMD, Scialli AR, Thompson K, Kim J. Critical evaluation of current developmental toxicity testing strategies: A case of babies and their bathwater. Birth Defects Res (Part B) 2011; 92(5):395-403.
DownloadChambers C, Scialli AR. Teratogenesis and environmental exposure. In Creasy RK, Resnik R, Iams JD, Lockwood CJ, Moore TR, Greene MF. Creasy & Resnik’s Maternal-Fetal Medicine 7th ed. Philadelphia: Elsevier Saunders; 2014: 465–472.
DownloadDamkier P, Scialli AR, Lusskin SI. Acetaminophen in prgnancy and adverse childhood neurodevelopment. JAMA Pediatrics 2017; doi:10.1001/jamapediatrics.2016.5049
DownloadDaston GP, Beyer BK, Carney EW, Chapin RE, Friedman JM, Piersma AH, Rogers JM, Scialli AR. Exposure-based validation list for developmental toxicity screening assays. Birth Defects Res (Part B) 2014;101:423–428.
DownloadDaston GP, Chapin RE, Scialli AR, Piersma AH, Carney EW, Rogers JM, Friedman JM. A different approach to validating screening assays for developmental toxicity. Birth Defects Res (Part B) 2010;89:526–530.
DownloadDekant W, Bridges J, Scialli AR. A quantitative weight of evidence assessment of confidence in modes-of-action and their human relevance. Regul Toxicol Pharmacol 2017;90:51–71.
DownloadDekant W, Scialli AR, Plotzke K, Klaunig JE. Biological relevance of effects following chronic administration of octamethylcyclotetrasiloxane (D4) in Fischer 344 rats, Toxicol Lett 2017;279S:42–53.
DownloadDeSesso JM, Scialli AR. Bone development in laboratory mammals used in developmental toxicity studies. Birth Defects Res 2018; https://doi.org/10.1002/bdr2.1350
DownloadDeSesso J, Harris S, Scialli A, Williams A. Systematic assessment of quaternary ammonium compounds (QUATS) for the potential to elicit developmental . and reproductive effects. Birth Defects Res 2021;113:1484–1511 DOI: 10.1002/bdr2.1963
DownloadDeSesso JM, Scialli AR, White TEK, Breckenridge CB. Multigeneration reproduction and male developmental toxicity studies on atrazine in rats. Birth Defects Res (Part B) 2014; DOI: 10.1002/bdrb.21106
DownloadFugh-Berman AJ, Scialli AR, Bell AM. Why lunch matters: Assessing physicians’ perceptions about industry relationships. J Cont Ed Health Prof 2010;30(3):197–204.
DownloadGarey JD, Damker P, Scialli AR, Lusskin S, Braddock SR, Chouchana L, Cleary B, Conover EA, Diav-Citrin O, Dragovich RS, Garcia-Bournissen F, Hodson K, Kennedy D, Lamm SH, Lavigne SA, Običan SG, Panchaud A, Perrotta K, Romeo AN, Schechtman S, Weber-Schoendorfer C. Paternal valproate treatment and risk of childhood neurodevelopmental disorders: Precautionary regulatory measures are insufficiently substantiated. Birth Defects Res 2024; 116:e2392 https://doi.org/10.1002/bdr2.2392
DownloadGarey JD, Lusskin SI, Scialli AR. Teratogen update: Amphetamines. Birth Defects Res 2020;112:1161–1182. doi: 10.1002/bdr2.1774
DownloadGoodman M, Mandel JS, DeSesso JM, Scialli AR. Atrazine and pregnancy outcomes: A systematic review of epidemiologic evidence. Birth Defects Res (Part B) 2014; DOI: 10.1002/bdrb.21101
DownloadHuo S, Scialli AR, McGarvey S, Hill E, Tügertimur B, Hogenmiller A, Hirsch AI, Fugh-Berman A. Treatment of men for “low testosterone”: A systematic review. PLOS ONE 2016; DOI:10.1371/journal.pone.0162480.
DownloadHyoun SC, Običan SG, Scialli AR. Teratogen update: Methotrexate. Birth Defects Res (Part A) 2012; 94(4):187-207.
DownloadJean PA, Plotzke KP, Scialli AR. Chronic toxicity and oncogenicity of decamethylcyclopentasiloxane in the Fischer 344 rat. Regul Toxicol Pharmacol 2016; 74:S57–S56.
DownloadKim J, Scialli AR. Thalidomide: The tragedy of birth defects and the effective treatment of disease Toxicological Sciences 2011; 122(1):1–6. doi: 10.1093/toxsci/kfr088
DownloadKlaunig JE, Dekant W, Plotzke K, Scialli AR. Biological relevance of decamethylcyclopentasiloxane (D5) induced rat uterine endometrial adenocarcinoma tumorigenesis: Mode of action and relevance to humans. Regul Toxicol Pharmacol 2016;74:S44–S56.
DownloadLaufersweiler MC, Gadagbui B, Baskerville-Abraham IM, Maier A, Willis A, Scialli AR, Carr GJ, Felter SP, Blackburn K, Daston G. Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern. Regul Toxicol Pharmacol; 2012; 62:160–182.
DownloadMahadevan U, Levy G, Gensler L, Ali M, Lacerda AP, Wegrzyn L, Palac H, Bhutani-Jacques T, Long M, Clowse MEB, Kimball AB, Chambers C, Scialli AR. Pregnancy outcomes in patients treated with upadacitinib: Analysis of data from clinical trials and postmarketing reports. Drug Safety 2024. https://doi.org/10.1007/s40264-024-01454-0
DownloadObičan SG, Finnell RH, Mills JL, Shaw GM, Scialli AR. Folic acid in early pregnancy. A public health success story. FASEB J 2010; 24:4167–4174.
DownloadObičan SG, Jahnke GD, Soldin OP, Scialli AR. Teratology Society Public Affairs Committee position paper: Iodine deficiency in pregnancy. Birth Defects Res (Part A) 2012; 94(9):677–682.
DownloadObičan SG, Scialli AR. Teratogenic exposures. Am J Med Genet (Part C) 2011;157(3):150–169.
DownloadRobinson C, Van Boxmeet J, Tilson H, Scialli A, Vanchere JA, Ides E, Sawlwin D, Molrine D, Hohenboken M, Edelman J, Albano J. Outcomes in pregnant persons immunized with a cell-based quadrivalent inactivated influenza vaccine: A propsective observational cohort study. Vaccines 2022;10:1600. https://doi.org/10.3390/vaccines10101600
DownloadRobinson C, Oberye J, van Boxmeer J, Albano J, Tilson H, Scialli A, Vanchiere JA, Ides E, Sawlwin D, Hohenboken M, Edelman J. A prospective cohort study on pregnancy outcomes of persons immunized with a seasonal quadrivalent inactivated influenza vaccine during pregnancy. Vaccines 2022;10:1577. https://doi.org/10.3390/vaccines10101577.
DownloadScialli AR. Decamethylcyclopentasiloxane (D5) should not be considered toxic to reproduction. Toxics. 2023 preprint DOI: 10.20944/preprints202307.1454.v1
DownloadScialli AR. Decamethylcyclopentasiloxane developmental neurotoxicity testing. Reprod Toxicol 2024;123:108521 https://doi.org/10.1016/j.reprotox.2023.108521
DownloadScialli AR. Developmental and reproductive toxicity evaluation under the European Union REACH regulations. In Hood RD, ed., Developmental and Reproductive Toxicology, Third Ed. New York: Informa Healthcare; 2012:730–735.
DownloadScialli AR. Serotonin reuptake inhibitors and heart defects. Reprod Toxicol 2016;63:140–141.
DownloadScialli AR. Teratogen? Birth Defects Res 2020;112)15):1103–1104. DOI: 10.1002/bdr2.1746
DownloadScialli AR. The National Birth Defects Prevention Study: How to communicate data. Semin Fetal Neonat Med 2014;19:170–176.
DownloadScialli AR, Ang R, Breitmeyer J, Royal MA. A review of the literature on the effects of acetaminophen on pregnancy outcome. Reprod Toxicol 2010; 495–507.
DownloadScialli AR, Ang R, Breitmeyer J, Royal MA. Childhood asthma and use during pregnancy of acetaminophen. A critical review. Reprod Toxicol 2010; 508–519.
DownloadScialli AR, Bonde JP, Brüske-Hohlfeld I, Culver D, Li Y, Sullivan FM. An overview of male reproductive studies of boron with an emphasis on studies of highly exposed Chinese workers. Reprod Toxicol 2010;29:10–24.
DownloadScialli AR, Clark RV, Chapin R. The predictivity of non-clinical male reproductive findings for human effects. Birth Defects Res 2017; doi: 10.1002/bdr2.1102
DownloadScialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL, DeLise AM, Hui JY, Moffat GJ, Stewart J, Thompson KE. Potential seminal transport of pharmaceuticals to the conceptus. Reprod Toxicol 2015;58:213–221.
DownloadScialli AR, Daston G, Chen C, Coder PS, Euling SY, Foreman J, Hoberman AM, Hui J, Knudsen T, Makris SL, Morford L, Piersma AH, Stanislaus D, Thompson KE. Rethinking developmental toxicity testing: Evolution or revolution. Birth Defects Res 2018; DOI: 10.1002/bdr2.1212.
DownloadScialli AR, DeSesso JM, Breckenridge CB. Developmental toxicity studies with atrazine and its major metabolites in rats and rabbits. Birth Defects Res (Part B) 2014; DOI: 10.1002/bdrb.21099
DownloadScialli AR, Guikema AJ. REACH and reproductive and developmental toxicology: Still questions. Syst Biol Reprod Med 2012;58(1):63–69.
DownloadScialli AR, Saavedra K, Fugh-Berman A. The benefits and risks of adherence to medical therapy. JoSPI (Journal of Scientific Practice and Integrity). 2021; https://doi.org/10.35122/001c.21386
DownloadScialli AR, Watkins DK, Ginevan ME. Agent Orange exposure and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in human milk. Birth Defects Res (Part B). 2015; 104:129–139.
DownloadWyszynski SD, Bhattacharya M, Martinez-Perez O, Scialli AR, Tassinari M, Bar-Zeev N, Renz C, Hernández-Díaz S. The COVID-19 Vaccines International Pregnancy Exposure Registry (C-VIPER): Protocol and methodological considerations. Drug Safety 2023; https://doi.org/10.21007/s40264-022-01271-3.
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Tony Scialli is a specialist in reproductive and developmental toxicology and in obstetrics and gynecology. In addition to his consulting services, he is Clinical Professor of Obstetrics and Gynecology at George Washington University School of Medicine and Adjunct Professor of Obstetrics and Gynecology and of Pharmacology and Physiology at Georgetown University Medical Center.
